Use of continuous positive airway pressure reduces airway reactivity in adults with asthma

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Use of continuous positive airway pressure reduces airway reactivity in adults with asthma.

Asthma is characterised by airway hyperreactivity, which is primarily treated with β-adrenergic bronchodilators and anti-inflammatory agents. However, mechanical strain during breathing is an important modulator of airway responsiveness and we have previously demonstrated in animal models that continuous positive airway pressure (CPAP) resulted in lower in vivo airway reactivity. We now evaluat...

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Chronic continuous positive airway pressure (CPAP) reduces airway reactivity in vivo in an allergen-induced rabbit model of asthma.

Previous studies have demonstrated that chronic mechanical strain produced by continuous positive airway pressure (CPAP) reduces in vivo airway reactivity in rabbits and ferrets. For CPAP to potentially have a therapeutic benefit for asthmatic subjects, the reduction in airway responsiveness would need to persist for 12-24 h after its discontinuation, require application for only part of the da...

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Comparison of Nasal Continuous Positive Airway Pressure Therapy with and without Prophylactic Surfactant in Preterm Neonates

Background: Preterm labor is at risk for respiratory distress syndrome (RDS) and sometimes requires to mechanical ventilation (MV) and surfactant therapy. Continuous positive airway pressure (CPAP) and Nasal Continuous positive airway pressure (NCPAP) are the methods of respiratory support especially for using in RDS of neonates. In other method surfactant is administered to babies via tracheal...

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Continuous Positive Airway Pressure for Adults with Obstructive Sleep Apnea.

www.thoracic.org C LI P A N D C O P Y OSA patients wake up often throughout the night (although they may not remember doing so) and thus can be very tired during the daytime. In addition, each stoppage in breathing can lead to falls in oxygen level and a stress release of adrenaline, both of which can contribute to high blood pressure and put a strain on the heart. Left untreated, this situatio...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2012

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.00059712